Tag Archives: Vaccine

Ebola Vaccine, Ready for Test, Sat on the Shelf

By

GALVESTON, Tex. — Almost a decade ago, scientists from Canada and the United States reported that they had created a vaccine that was 100 percent effective in protecting monkeys against the Ebola virus. The results werepublished in a respected journal, and health officials called them exciting. The researchers said tests in people might start within two years, and a product could potentially be ready for licensing by 2010 or 2011.

It never happened. The vaccine sat on a shelf. Only now is it undergoing the most basic safety tests in humans — with nearly 5,000 people dead from Ebola and an epidemic raging out of control in West Africa.

Its development stalled in part because Ebola is rare, and until now, outbreaks had infected only a few hundred people at a time. But experts also acknowledge that the absence of follow-up on such a promising candidate reflects a broader failure to produce medicines and vaccines for diseases that afflict poor countries. Most drug companies have resisted spending the enormous sums needed to develop products useful mostly to countries with little ability to pay.

Read more » The New York Times

 

Measles Vaccine Wipes Out Cancer in Groundbreaking Test

By Stan Schroeder

Researchers at the Mayo Clinic have completed a groundbreaking new test: They knocked widespread blood cancer into remission with a single massive blast of measles vaccine.

Stacy Erholtz, who was suffering from an advanced stage of blood cancer, recovered thanks to an intravenous injection of the measles virus, which was sufficient to overwhelm the cancer’s natural defenses, the StarTribune reports

As far as clinical trials go, this was a small test because it only had two subjects. But lead researcher Dr. Stephen Russell told StarTribune it’s a promising start.

“It’s a landmark. We’ve known for a long time that we can give a virus intravenously and destroy metastatic cancer in mice. Nobody’s shown that you can do that in people before,” he said.

The viruses bind to cancer cells and use them to replicate. The process destroys the cells, and the body’s immune system attacks what’s left since it’s marked as viral material. This test also gave doctors a benchmark for the virus dose needed to reduce cancer in patients — 100 billion infectious units instead of the standard 10,000 units.

There are still hurdles to overcome — like the body’s own defenses. Once the immune system has experience fighting a virus, it’s not effective a second time. The body attacks it before it can begin taking over cancer cells.

Doctors will also need to do more testing on more patients. They plan to expand their trials by September.

Courtesy: Mashable
http://mashable.com/2014/05/15/measles-vaccine-fight-cancer/?utm_cid=mash-com-fb-main-link

New vaccine for High blood pressure

The blood pressure injection you need just twice a year

Jab blocks effects of a hormone in body that triggers high blood pressure

So far been tested only on rats, and successfully lowered high readings

By Pat Hagan

A vaccine given just twice a year could keep high blood pressure at bay. The jab could free millions of people from the burden of taking pills every day to keep their condition under control.

It works by blocking the effects of a hormone in the body that triggers high blood pressure by making the muscles surrounding blood vessels contract.

This chemical, called angiotensin 2, forces muscles to keep contracting, which makes blood vessels narrower and increases the pressure on vessel walls – raising the risk of a heart attack or stroke. The vaccine prompts the immune system to release antibodies that stop angiotensin 2 from reaching the muscles.

The experimental jab, which has so far been tested only on rats, successfully lowered their high readings and kept blood pressure at lower, safer levels for at least six months before a booster was needed.

Researchers at Osaka University in Japan, where the jab is being developed, hope to carry out trials on humans within the next two years. High blood pressure, or hypertension, affects one in five adults in the UK and is thought to be responsible for half of all heart attacks and strokes.

It develops when blood vessel walls lose their ability to stretch and dilate, restricting the flow of blood through the body.

In some patients, it’s possible to get readings down by eating less salt and taking more exercise, but millions need pills to control it.

One of the main treatments is a class of drugs known as angiotensin  2 receptor blockers (ARBs).

These work by stopping angiotensin 2 from locking on to receptors on the outside of muscle cell walls and thereby triggering the dangerous contractions that cause high blood pressure.

Read more: http://www.dailymail.co.uk/health/article-2543019/The-blood-pressure-injection-need-just-twice-year.html#ixzz2rSz0Z86u

Herpes simplex virus 1, Genital Herpes- 2, varicella zoster virus and cold sores

Herpes simplex virus 1, 2, (in Sindhi language Tap Mut or Sur Sur), varicella zoster and cold sores infections are all belongs the Herpes virus group. From centuries, viruses are the enemies of human kind. Genital Herpes is a sexually transmitted disease (STD). This disease is responsible for the painful, irritating and embarrassing outbreaks. The virus persists in the nerve and it considered incurable, though there is much you can do to inactivate the virus. Harpies Simplex Virus- 1 (HSV-1) is causes cold sores on the lips and the cornea of eye. HSV-2 causes genital occurrences. Harpies Simplex Virus (HSV-2) reactivated by immune deficiency, diabetes, cancer, depression, dementia, Alzheimer’s disease, bipolar disorder, other disorders, anxiety, hormonal changes, during periods (menses), physical or emotional stress. Periods (menses) also increase the activity of HSV. Therefore, be cautious during menses take antiviral medicines such as acyclovir, Famcyclovir or Valacyclovir or Zovirex.

Now the scientists know that human immune system is so powerful to overcome the Herpes simplex accordingly.

This may help to keep prevent from outbreaks:

Avoid: Almonds, Wall nuts, chocolate, peanuts, Peas, sunflower seeds, other kinds of nuts’ and seeds’ protein trigger the Herpes virus re-occurrences. Corn based products (corns, pop corns, corn oil) are high in arganine and increase the HSV activity in cells. Those who are getting re-occurrences of Herpes simplex infection frequently should avoid eating all kinds of nuts and chocolate. Avoid tomatoes and green peas, and also avoid cooking in vegetable oil, coconut oil, corn oil, canola oil too. Use butter for cooking. Avoid foods that contain arganine. Chocolate is full of arganine. Avoid sugar and sugar products (Sweets).

This may help to keep your immune system high, it will help prevent outbreaks:

This may help in Genital Harpies Simplex virus I, II (Tap mut or Sur Sur) and varicella Zoster- Take extra vitamin C such as 500 mg vitamin C two times a day every day to boost your immune system, chewable vitamin C may damage your teeth therefore take non-chewable vitamin C and Vitamin E 400 IU daily whole of life.) Vitamin C works better than any anti-viral pills (acyclovir, Famcyclovir, Valacyclovir). Take Magnicium 10mg, B-complex 25 mg daily will help immune system, Calcium 100mg daily. Lemons are good source of vitamin C and fish is good source of vitamin E.

Lysine is good to prevent form Herpes Simplex virus re-occurrence. Lentils and legumes are the best source of lysine. Bee propolis with lemon ointment (lemon bam) also helps to prevent from re-occurring. Turmeric (in Hindi language Haldi) and garlic also helps to reduce re-occurring of harpes outbreaks. Mix water in Turmeric powder and make paste of turmeric put some drops of lemon and apply the affected area. Boiled eggs are good source of lysine, eat boiled eggs to prevent Herpes. Garlic and Aloevera has some effectiveness against Herpes.

Cut off refine carbohydrates/carbs, starchy foods, Sugar and sugar products, rice and rice products, potato and potato products. Eat deep water fish, drink fresh clean water and yogurt early in the morning every day. Add red onion, garlic, ginger, and turmeric in your food. Mix the lemon drops and tincture together in equal parts and apply the affected area.

Do not burst the blister/bubble of harpies with pin or any thing. Wash the affected area with hydrogen per oxide available at grocery stores and pharmacies with out prescription. Try not to touch the affected area with bare hands. Use gloves, or tissue paper to save your hand. Do not expose the affected area to sun or sun shine. Eat fresh washed raw green leafy and colorful vegetable and fruits and drink moderate amount of fresh clean water every day.

If the blisters from Herpes appear close to the eye or occur on the tip or side of the nose, see a doctor immediately. Because Herpes can end up causing vision problems if it involves nerves around the eye.

Source » Internet

For more information » http://herpesvaccine.scienceblog.com/2013/06/15/purpose-of-the-herpes-vaccine-blog/

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Zostavax vaccine » http://www.cbc.ca/news/health/shingles-vaccine-effectiveness-varies-with-age-1.1393815