Tag Archives: injection

New vaccine for High blood pressure

The blood pressure injection you need just twice a year

Jab blocks effects of a hormone in body that triggers high blood pressure

So far been tested only on rats, and successfully lowered high readings

By Pat Hagan

A vaccine given just twice a year could keep high blood pressure at bay. The jab could free millions of people from the burden of taking pills every day to keep their condition under control.

It works by blocking the effects of a hormone in the body that triggers high blood pressure by making the muscles surrounding blood vessels contract.

This chemical, called angiotensin 2, forces muscles to keep contracting, which makes blood vessels narrower and increases the pressure on vessel walls – raising the risk of a heart attack or stroke. The vaccine prompts the immune system to release antibodies that stop angiotensin 2 from reaching the muscles.

The experimental jab, which has so far been tested only on rats, successfully lowered their high readings and kept blood pressure at lower, safer levels for at least six months before a booster was needed.

Researchers at Osaka University in Japan, where the jab is being developed, hope to carry out trials on humans within the next two years. High blood pressure, or hypertension, affects one in five adults in the UK and is thought to be responsible for half of all heart attacks and strokes.

It develops when blood vessel walls lose their ability to stretch and dilate, restricting the flow of blood through the body.

In some patients, it’s possible to get readings down by eating less salt and taking more exercise, but millions need pills to control it.

One of the main treatments is a class of drugs known as angiotensin  2 receptor blockers (ARBs).

These work by stopping angiotensin 2 from locking on to receptors on the outside of muscle cell walls and thereby triggering the dangerous contractions that cause high blood pressure.

Read more: http://www.dailymail.co.uk/health/article-2543019/The-blood-pressure-injection-need-just-twice-year.html#ixzz2rSz0Z86u

China executes Pakistani man on drugs charges

China has executed a Pakistani man, Zahid Husain Shah, despite last-ditch appeals for clemency, his family says.

Mr Shah, 35, was arrested in 2008 and was convicted last year of drug smuggling. He was put to death by lethal injection in Shanghai on Wednesday morning.

Human rights groups had called on Beijing to stop the execution and urged Islamabad to take up appeals on his behalf. There was no comment from either government.

Relatives were allowed one last meeting with Mr Husain at Shanghai Detention Centre on Wednesday morning.

His cousin, Tasneem Fatima, told the BBC the family expects to travel back to Pakistan later this week, once his body has been returned to them. The last thing he told her was that he was innocent, she said.

Four other Pakistanis arrested with Mr Shah were sentenced to life imprisonment. According to Mr Husain’s relatives, he was framed for a crime he did not commit.

“Executing someone for drug-related offences violates internationally accepted standards for imposing the death penalty,” said Sam Zarifi, Amnesty International’s Asia-Pacific director.

The human rights group argues that no-one sentenced to death receives a fair trial in China, where thousands of executions for drug trafficking take place every year, more than the rest of the world combined.

Courtesy: → BBC