Tag Archives: benchmark

Measles Vaccine Wipes Out Cancer in Groundbreaking Test

By Stan Schroeder

Researchers at the Mayo Clinic have completed a groundbreaking new test: They knocked widespread blood cancer into remission with a single massive blast of measles vaccine.

Stacy Erholtz, who was suffering from an advanced stage of blood cancer, recovered thanks to an intravenous injection of the measles virus, which was sufficient to overwhelm the cancer’s natural defenses, the StarTribune reports

As far as clinical trials go, this was a small test because it only had two subjects. But lead researcher Dr. Stephen Russell told StarTribune it’s a promising start.

“It’s a landmark. We’ve known for a long time that we can give a virus intravenously and destroy metastatic cancer in mice. Nobody’s shown that you can do that in people before,” he said.

The viruses bind to cancer cells and use them to replicate. The process destroys the cells, and the body’s immune system attacks what’s left since it’s marked as viral material. This test also gave doctors a benchmark for the virus dose needed to reduce cancer in patients — 100 billion infectious units instead of the standard 10,000 units.

There are still hurdles to overcome — like the body’s own defenses. Once the immune system has experience fighting a virus, it’s not effective a second time. The body attacks it before it can begin taking over cancer cells.

Doctors will also need to do more testing on more patients. They plan to expand their trials by September.

Courtesy: Mashable
http://mashable.com/2014/05/15/measles-vaccine-fight-cancer/?utm_cid=mash-com-fb-main-link

Israeli hardliners have started a massive campaign to undermine Obama’s stand that peace can only come with a truly independent Palestinian state

Obama Sees ’67 Borders as Starting Point for Peace Deal

By MARK LANDLER and STEVEN LEE MYERS

WASHINGTON — President Obama, seeking to capture a moment of epochal change in the Arab world, began a new effort on Thursday to break the stalemate in the Israeli-Palestinian conflict, setting out a new starting point for negotiations on the region’s most intractable problem.

A day before the arrival in Washington of Prime Minister Benjamin Netanyahu of Israel, Mr. Obama declared that the prevailing borders before the 1967 Arab-Israeli war — adjusted to some degree to account for Israeli settlements in the West Bank — should be the basis of a deal. While the 1967 borders have long been viewed as the foundation for a peace agreement, Mr. Obama’s formula of land swaps to compensate for disputed territory created a new benchmark for a diplomatic solution.

Mr. Obama’s statement represented a subtle, but significant shift, in American policy. And it thrust him back into the region’s most nettlesome dispute at a time when conditions would seem to make reaching a deal especially difficult.

The Israeli government immediately protested, saying that for Israel to return to its pre-1967 borders would leave it “indefensible.” Mr. Netanyahu held an angry phone conversation with Secretary of State Hillary Rodham Clinton on Thursday before the speech, officials said, in which he demanded that the president’s reference to 1967 borders be cut.

Israeli officials continued to lobby the administration until right before Mr. Obama arrived at the State Department for the address. White House officials said he did not alter anything under Israeli pressure ….

Read more : The New York Times